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Table 1 Baseline demographic, lifestyle and clinical characteristics of the study participants during follow-up (n = 2,067). Data are weighted percentages for categorical variables and weighted means (standard errors) for normally distributed continuous variables.

From: Association between variations in the TLR4gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol

 

Cases (N = 498)

Non-cases (N = 1569)

p-value*

Demographic

   

Sex = male [%]

61.7

53.2

<0.001

Age [yrs]

56.0 (0.4)

51.6 (0.3)

<0.001

Clinical

   

Body Mass Index [kg/m2]

30.0 (0.2)

26.7 (0.1)

<0.001

Systolic Blood Pressure [mmHg]

142.2 (0.8)

132.7 (0.5)

<0.001

Diastolic Blood Pressure [mmHg]

85.3 (0.5)

81.5 (0.3)

<0.001

History of actual hypertension [%]

66.5

39.8

<0.001

History of myocardial infarction [%]

5.0

1.9

0.003

Total cholesterol [mg/dl]

247.4 (2.0)

235.9 (1.1)

<0.001

HDL cholesterol [mg/dl]

47.9 (0.6)

57.6 (0.4)

<0.001

Ratio TC/HDL-C

5.6 (0.1)

4.5 (0.0)

<0.001

Lifestyle

   

Smoking status [%]

  

0.002

Current smoker

26.9

24.2

 

Former smoker

33.3

27.2

 

Never smoker

39.8

48.6

 

Frequency of exercise [%]

  

<0.001

Inactive

69.1

58.3

 

Active

30.9

41.7

 

Alcohol consumption† [%]

  

0.112

0 g/d

32.1

28.5

 

0–39.9/0–19.9 g/d

39.4

44.6

 

≥ 40/20 g/d

28.5

26.9

 

Survey ‡

  

<0.001

S1 [%]

36.5

28.9

 

S2 [%]

39.4

36.1

 

S3 [%]

24.1

35.0

 
  1. * t-test for continuous variables and chi-square-test for categorical variables; † Men: 0 g/d, 0–39.9 g/d, ≥40 g/d; Women: 0 g/d, 0–19.9 g/d, ≥20 g/d; ‡ Independent cross-sectional study