Figure 3

(A) Reduced penetrance of LQTS phenotype and effect of exercise on QTc. Mean QTc for carriers with mutation L187P and 11 non-carriers (left) and mean QTc for mutation carriers before (resting state) and during exercise (right). (B, C) Example of reduced penetrance of LQTS phenotype at baseline. Initial ECG (B) and ECG after 15-min exercise (C) are shown for a 29 year old, male, asymptomatic mutation L187P carrier.