Table 3 Variants in 5'- and 3'-UTRs
From: Prevalence of variations in melanoma susceptibility genes among Slovenian melanoma families
| Â | 3'UTR and 5'UTR VARIANTS | Â | |
|---|---|---|---|
| Â | Positive cases | Â | |
Location | CDKN2A nucletide change | Pts and healthy relatives (n = 35) | Healthy controls (n = 54) |
3'-UTR | 500C > G | 22 | 13 |
3'-UTR | 540C > T | 12 | 2 |
5'-UTR | -191A > G | 38 | 31 |
| Â | Â | Pts with CM (n = 28) | Healthy controls (n = 54) |
500C > G | heterozygous | 17 | 12 |
| Â | homozygous | 2 | 1 |
540C > T | heterozygous | 11 | 2 |
| Â | homozygous | 1 | 0 |
-191A > G | heterozygous | 26 | 28 |
| Â | homozygous | 8 | 3 |