Table 6 Allele frequency distribution and association study in ADAM33
Name | SNP | Minor allele frequency | P-value | Permutation p-value | Odds ratio (95% CI) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
AR (n = 128) | AS (n = 181) | CTR (n = 151) | AR vs CTR | AS vs CTR | AR vs CTR | AS vs CTR | AR vs CTR | AS vs CTR | ||
Rs2787094 | G/C | 0.406 | 0.514 | 0.146 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | 0.25(0.17–0.37) | 0.16(0.11–0.24) |
rs2280089 | A/G | 0.231 | 0.102 | 0.136 | 0.0037 | 0.1812 | 0.0279 | 1.91(1.23–2.96) | ||
rs2280090 | A/G | 0.094 | 0.158 | 0.04 | 0.0097 | <0.0001 | <0.0001 | 4.52(2.37–8.59) | ||
rs2280091 | G/A | 0.348 | 0.437 | 0.129 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | 0.28(0.18–0.42) | 0.19(0.13–0.28) |
rs3918396 | G/A | 0.109 | 0.113 | 0.136 | 0.3454 | 0.3802 | ||||
rs612709 | A/G | 0.063 | 0.121 | 0.036 | 0.1526 | <0.0001 | 0.0016 | 3.66(1.86–7.22) | ||