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Table 4 Genotype frequency distribution and association study in ADAM33 between AR and CTR

From: Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population

Genotype

Frequency, no.(%)

x2 P value

Odds ratio

  

AR(n = 128)

CTR(n = 151)

 

(95% CI)

rs2787094

CC

46(35.94)

113(74.84)

<0.0001

0.19(0.11–0.32)

 

CG

60(46.88)

32(21.19)

<0.0001

3.28(1.95–5.53)

 

GG

22(17.18)

6(3.97)

0.0003

5.02(1.97–12.80)

rs2290089

AA

4(3.13)

0

0.0432

 
 

AG

51(39.84)

41(27.15)

0.0246

1.78(1.07–2.94)

 

GG

73(57.03)

110(72.85)

0.0056

0.49(0.30–0.82)

rs2280090

AA

0

0

  
 

AG

24(18.75)

12(7.95)

0.0073

2.67(1.28–5.59)

 

GG

104(81.25)

139(92.05)

0.0073

0.37(0.18–0.78)

rs2280091

AA

56(43.75)

117(77.48)

<0.0001

0.23(0.13–0.38)

 

AG

55(42.97)

29(19.21)

<0.0001

3.17(1.86–5.41)

 

GG

17(13.28)

5(3.31)

0.0021

4.47(1.60–12.49)

rs3918396

AA

100(78.12)

110(72.85)

0.3086

 
 

AG

28(21.88)

41(27.15)

0.3086

 
 

GG

0

0

  

rs612709

AA

0

0

  
 

AG

16(12.5)

11(7.28)

0.142

 
 

GG

112(87.5)

140(92.72)

0.142