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Table 1 Allelic and genotypic frequencies for the TCF7L2 variants in TCP patients and controls of different ethnic groups

From: TCF7L2 gene polymorphisms do not predict susceptibility to diabetes in tropical calcific pancreatitis but may interact with SPINK1 and CTSBmutations in predicting diabetes

SNP (NCBI 36.2&)

Allele

Dravidian

Indo-Europeans

Total

Genotype

Dravidian@

Indo-Europeans@

Total@

  

Patients

Controls

Patients

Controls

Patients

Controls

 

Patients

Controls

Patients

Controls

Patients

Controls

  

n = 333

n = 259

n = 145

n = 402

n = 478

n = 661

 

n = 333

n = 259

n = 145

n = 402

n = 478

n = 661

rs7903146 (114748339)

C

0.71

0.70

0.72

0.71

0.73

0.71

CC

175 (52.6)

130 (50.2)

78 (53.8)

207 (51.5)

253 (53.0)

337 (51.0)

        

CT

126 (37.8)

104 (40.2)

53 (36.6)

160 (39.8)

179 (37.3)

264 (39.9)

 

T

0.29

0.30

0.28

0.29

0.27

0.29

TT

32 (9.6)

25 (9.7)

14 (9.7)

35 (8.7)

46 (9.6)

60 (9.1)

  

n = 332

n = 180

n = 144

n = 402

n = 476

n = 582

 

n = 332

n = 180

n = 144

n = 402

n = 476

n = 582

rs12255372 (114798892)

G

0.77

0.78

0.78

0.78

0.77

0.78

GG

201 (60.5)

108 (60.0)

88 (61.1)

244 (60.7)

289 (60.7)

352 (60.5)

        

GT

110 (33.1)

64 (35.6)

48 (33.3)

135 (33.6)

158 (33.2)

199 (34.2)

 

T

0.23

0.22

0.22

0.22

0.23

0.22

TT

21 (6.3)

8 (4.4)

8 (5.6)

23 (5.7)

29 (6.1)

31 (5.3)

  1. SNP, single nucleotide polymorphism; n, number of individuals; &, Chromosome position according to National Centre for Biotechnology Information (NCBI), Build 36.2, contig accession number NT 030059.12; @, values in the parentheses indicate percentage genotype frequency