Common variants of the TCF7L2gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population

Table 1 Clinical characteristics of subjects studied

	Diabetic subjects	Control subjects
n	831	437
Gender (M/F)	450/381	219/218
Age at study (years)	56.9 ± 12.1	55.0 ± 11.8
Age at diagnosis (years)	49.6 ± 11.9	N/A^a
BMI (kg/m ² )	28.3 ± 4.7	28.1 ± 4.9^b
Waist circumference (cm)	102.4 ± 10.7	99.8 ± 13.1^b
Systolic blood pressure (mm Hg)	140.5 ± 20.9	135.7 ± 20.4^b
Diastolic blood pressure (mm Hg)	84.1 ± 11.5	85.1 ± 12.1^b
HDL cholesterol (mmol/l)	1.3 ± 0.5	ND^c
HbA1c (%)	8.3 ± 1.9	ND^c

Data are expressed as means ± standard deviation (SD). Mean age of control subjects at the time of the study was significantly greater than the mean age at diagnosis of the case subjects (p = 4.37 × 10^-13). ^aN/A = not applicable. ^bBMI, waist circumference and blood pressure measurements were only available for 252 control subjects. ^cND = data not determined.

ISSN: 1471-2350