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Table 2 HLA-DQB1 distribution in Mexican Mestizo patients with narcolepsy and in healthy controls.

From: Association of narcolepsy-cataplexy with HLA-DRB1 and DQB1in Mexican patients: A relationship between HLA and gender is suggested

Locus

Total Patients

Total Controls

     

DQB1*

N = 32

AF%

N = 203

AF%

X2Y

OR

(CI)

p

pc

0201

8

12.5

43

10.6

0.1

    

0301

16

25.0

100

24.6

0.0

    

0302

8

12.5

111

27.3

5.7

0.4

(0.2–0.9)

0.017

NS

0303

2

3.1

5

1.2

0.4

    

0402

5

7.8

60

14.8

1.7

    

0501

2

3.1

35

8.6

1.6

    

0502

0

0

5

1.2

0.1

    

0503

0

0

5

1.2

0.1

    

0601

0

0

4

1

0.0

    

0602

21

32.8

22

5.4

46.7

8.4

(4.3–16.6)

<0.0001

<0.0001

0603

0

0

7

1.7

0.3

    

0604

0

0

7

1.7

0.3

    

0605

1

1.6

1

0.2

0.2

    

0609

1

1.6

1

0.2

0.2

    
  1. AF: allele frequency; X2Y: Chi2 value with Yates correction; OR: Odds Ratio; CI: Confidence Interval; pc: Bonferroni correction (the p value was multiplied by the total number of alleles tested); NS: Not significant.
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BMC Medical Genetics

ISSN: 1471-2350

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