Effects of common haplotypes of the ileal sodium dependent bile acid transporter gene on the development of sporadic and familial colorectal cancer: A case control study

Table 3 Genotype frequencies of SLC10A2 tagging SNPs

Tagging SNP	Variant	Genotype frequency			Armitage trend test
		Familial CRC	Sporadic CRC	'Hyper-normal' controls
rs279941	GG	0.74	0.82	0.76	*p = 0.78
	GT	0.25	0.17	0.22	^#p = 0.27
	TT	0.01	0.01	0.02
rs183963	AA	0.46	0.39	0.43	*p = 0.56
	AT	0.39	0.49	0.41	^#p = 0.97
	TT	0.15	0.12	0.15
rs157266	GG	0.74	0.80	0.76	*p = 0.87
	GA	0.25	0.19	0.19	^#p = 0.23
	GT	0.01	0.02	0.05
rs1886927	GG	0.81	0.84	0.82	*p = 0.98
	GT	0.19	0.15	0.17	^#p = 0.67
	TT	0.00	0.01	0.01

* comparison of genotype frequencies between familial CRC and hypernormal controls
# comparison of genotype frequencies between sporadic CRC and hypernormal controls

ISSN: 1471-2350