Dinucleotide repeat polymorphism in Fms-like tyrosine kinase-1 (Flt-1) gene is not associated with preeclampsia

BMC Medical Genetics

Table 3 Genotype frequency of the Flt-1 (TG)_n polymorphism in normal controls and preeclamptic patients

Genotype	Controls	Patients	OR (95% CI)	p value
	n (%)	n (%)
(TG)₁₄/(TG)₁₄	91 (45.05)	65 (38.24)	1.11 (0.59–2.09)	0.746^a
(TG)₁₄/(TG)₂₁	76 (37.62)	71 (41.76)	0.85 (0.45–1.60)	0.613^b
(TG)₂₁/(TG)₂₁	6 (2.97)	11 (6.47)	0.43 (0.14–1.35)	0.143^c
Other	29 (14.36)	23 (13.53)	-	-
Combination	111 (54.95)	105 (61.77)	1.32 (0.87–2.01)	0.185^d

OR = odds ratios; CI = confidence interval.
Other, any genotypes other than the (TG)₁₄/(TG)₁₄, (TG)₁₄/(TG)₂₁, or (TG)₂₁/(TG)₂₁ genotype.
Combination, combined genotype [(TG)₁₄/(TG)₂₁+(TG)₂₁/(TG)₂₁+Other].
A p value was calculated using the Chi-Squared test or Fisher's exact test.
Significant value was taken at the level of p < 0.05.
^a(TG)₁₄/(TG)₁₄ versus Other.
^b(TG)₁₄/(TG)₂₁ versus Other.
^c(TG)₂₁/(TG)₂₁ versus Other.
^d(TG)₁₄/(TG)₁₄ versus Combination.

ISSN: 1471-2350