Figure 6From: Design considerations in a sib-pair study of linkage for susceptibility loci in cancer Effect of varying number of offspring proxies on power for families of three affected siblings. Effect of sample size and varying numbers of offspring proxies (O) on estimated power, families with three affected sibs, with only two available for genotyping (O = 0, 1, or 2), compared with families with all three affected sibs available for genotyping (S = 3).Back to article page