Figure 5From: Design considerations in a sib-pair study of linkage for susceptibility loci in cancer Effect of varying number of offspring proxies on power for families of two affected siblings. Effect of sample size and varying numbers of offspring proxies (1 or 2) on estimated power, families with two affected sibs, with only one available for genotyping (1 or 2), compared with families with both affected sibs available for genotyping (S = 2).Back to article page