Polymorphism | Genotype | Control group | PTC Cases | p* | OR$ | (95%CI) |
---|---|---|---|---|---|---|
CYP1A1 C4887A | Â | Â | Â | Â | Â | Â |
 | CC | 331 (64.8%) | 95 (47%) |  |  |  |
 | CA | 162 (31.7%) | 89 (44%) | < 0.0001 | 1.91 | (1.36–2.70) |
 | AA | 18 (3.5%) | 18 (10%) | < 0.001 | 3.48 | (1.74–6.96) |
 | CA+AA | 180 (35.2%) | 107 (53%) | < 0.0001 | 2.07 | (1.49–2.88) |
NAT2 G590A | Â | Â | Â | Â | Â | Â |
 | GG | 284 (55.4%) | 99 (50%) |  |  |  |
 | GA | 181 (35.3%) | 81 (41%) | 0.180 | 1.28 | (0.91–1.82) |
 | AA | 47 (9.2%) | 18 (9%) | 0.76 | 1.11 | (0.61–1.98) |
 | GA+AA | 228 (44.5%) | 99 (50%) | 0.21 | 1.25 | (0.90–1.73) |
GSTT1 | Â | Â | Â | Â | Â | Â |
 | P | 385 (75%) | 96 (46.37%) |  |  |  |
 | D | 128 (25%) | 111 (53.62%) | < 0.0001 | 3.48 | (2.48–4.88) |
GSTM1 | Â | Â | Â | Â | Â | Â |
 | P | 233 (45.4%) | 109 (53.7%) |  |  |  |
 | D | 280 (54.6%) | 94 (46.3%) | 0.047 | 0.72 | (0.52–0.99) |
GSTM1+GSTT1 | Â | Â | Â | Â | Â | Â |
 | P | 423 (82.8) | 159 (78.32%) |  |  |  |
 | D | 88 (17.2%) | 48 (23.64%) | 0.074 | 1.45 | (0.98–2.16) |