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Table 3 Genes in which a SNP has a p-value < 0.01 for the maternal-fetal incompatibility model in the pre-eclampsia dataset

From: Analytical approaches to detect maternal/fetal genotype incompatibilities that increase risk of pre-eclampsia

Gene Symbol

rs Number

Incompatibility model P-value

Additive Model P-value

% of Incompatibility

Odds Ratio1

95% CI1

   

Maternal effects

Fetal effects

Cases

Controls

  

LTA

2857713

0.0007

0.53

0.67

29.6

35.1

0.439

[0.273, 0.708]

IGF1R

28401726

0.0017

0.42

0.23

11.7

8.54

3.089

[1.530, 6.238]

VWF

216900

0.0037

0.15

0.86

28.9

17.9

2.104

[1.273, 3.480]

VWF

216321

0.0083

0.17

0.59

24.6

19.6

1.940

[1.185, 3.176]

COL4A2

2296849

0.0046

0.01

0.03

24.5

16.2

2.193

[1.274, 3.773]

COL4A2

421177

0.0054

0.02

0.22

32.2

23.2

1.952

[1.219, 3.125]

IGF1

5742620

0.0088

0.01

0.48

8

3.65

3.504

[1.371, 8.955]

IL2RA

10752175

0.0082

0.09

0.22

44.7

34.9

1.797

[1.163, 2.777]

  1. 1Model unadjusted for Maternal and Fetal Effects