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Table 3 Results of mitochondrial haplogroup association testing with ischemic stroke risk.

From: Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients

  Number of Individuals (%) Chi-square Test Logistic Regression Model
Haplogroup Controls Patients P-value OR [95% CI] P-value OR [95% CI]
H 118 (23.6) 116 (21.7) 0.454   0.432  
H1 125 (25.1) 91 (17.0) 0.001 0.61 [0.45–0.83] 0.007 0.57 [0.38–0.85]
V 13 (2.6) 12 (2.2) 0.707   0.861  
pre-HV/HV 8 (1.6) 26 (4.9) 0.003 3.14 [1.41–7.01] 0.008 4.68 [1.51–14.54]
J 9 (1.8) 9 (1.7) 0.883   0.122  
J1b 23 (4.6) 24 (4.5) 0.928   0.862  
T 56 (11.2) 65 (12.2) 0.637   0.249  
U 6 (1.2) 18 (3.4) 0.021 2.87 [1.13–7.28] 0.038 4.01 [1.08–14.90]
U4 13 (2.6) 16 (3.0) 0.705   0.286  
U5 24 (4.0) 34 (6.3) 0.278   0.048 2.17 [1.01–4.67]
U6a 10 (2.0) 10 (1.9) 0.877   0.71  
K1 27 (5.4) 28 (5.2) 0.903   0.184  
I 10 (2.0) 11 (2.1) 0.950   0.500  
X2b 7 (1.4) 9 (1.7) 0.714   0.789  
W 6 (1.2) 11 (2.1) 0.279   0.394  
L 25 (5.0) 34 (6.4) 0.348   0.913  
Other* 19 (3.8) 20 (3.7) -   -  
  1. Significant uncorrected P-values (< 0.05) are highlighted in bold. Crude and adjusted odds ratios (OR) and 95% confidence intervals (CI) are shown only for significantly associated haplogroups.
  2. *Given that the "Other" class includes an assortment of lineages not phylogeneticaly correlated, association tests were not performed.