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Table 3 Frequency of haplotypes in breast cancer cases and controls and p-values for their association with cancer as determined by haplotype trend regression.

From: Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP

  Breast cancer cases Breast cancer controls
Haplotype/Agegroup Young1) Old2) All ages All ages
RAI-3'd1s RAI-3'd3s RAI-3'4c 0.0353 (0.37)4 0.054 (0.002) 0.051 (0.003) 0.022
RAI-3'd1s RAI-3'd3s RAI-3'4t 0.001 (-) 0.002 (0.12) 0.002 (0.09) 0.000
RAI-3'd1s RAI-3'd3l RAI-3'4c 0.008 (0.12) 0.006 (0.11) 0.006 (0.07) 0.001
RAI-3'd1s RAI-3'3dl RAI-3'4t 0.712 (0.02) 0.631 (0.17) 0.642 (0.06) 0.597
RAI-3'd1l RAI-3'd3s RAI-3'4c 0.244 (0.006) 0.297 (0.003) 0.290 (0.0005) 0.379
RAI-3'd1l RAI-3'd3s RAI-3'4t 0.000 (-) 0.005 (0.04) 0.005 (0.01) 0.000
RAI-3'd1l RAI-3'd3l RAI-3'4c 0.000 (-) 0.000 (0.61) 0.000 (0.11) 0.000
RAI-3'd1l RAI-3'd3l RAI-3'4t 0.000 (0.69) 0.003 (0.48) 0.003 (0.57) 0.001
RAI intron8-2a RAI intron8-3a 0.259 (0.78) 0.209 (0.01) 0.216 (0.02) 0.271
RAI intron8-2a RAI intron8-3c 0.000 (0.89) 0.007 (0.13) 0.006 (0.13) 0.000
RAI intron8-2g RAI intron8-3a 0.69 (0.12) 0.701 (0.001) 0.699 (0.0007) 0.615
RAI intron8-2g RAI intron8-3c 0.051 (0.05) 0.084 (0.11) 0.079 (0.04) 0.113
  1. 1) Breast cancer before age 55
  2. 2) Breast cancer at age 55 or older
  3. 3) Haplotype frequency
  4. 4) P-value for haplotype frequency in comparison to the haplotype frequency of controls, all ages.