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Table 2 Association of breast cancer with two additional polymorphisms selected from those detected by sequencing.

From: Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP

Polymorphism N1cases N1controls IRR2(95% CI3) P-trend4
RAI-3'd1     
All ages     0.0008
   LL 38 59 1  
   SL 127 165 1.39 (0.81–2.38)  
   SS 200 150 2.44 (1.41–4.23)  
<55 yr     0.01
   LL 5 15 1  
   SL 18 25 1.46 (0.33–6.47)  
   SS 33 14 6.29 (1.49–26.61)  
55–60 yr     0.19
   LL 12 17 1  
   SL 45 63 1.72 (0.63–4.73)  
   SS 61 49 2.57 (0.88–7.48)  
>60 yr     0.12
   LL 21 27 1  
   SL 64 77 1.09 (0.52–2.60)  
   SS 106 87 1.73 (0.83–3.64)  
RAI -3'd2     
All ages     0.005
   LL 149 113 1  
   SL 168 199 0.62 (0.44–0.88)  
   SS 66 88 0.50 (0.32–0.79)  
  1. 1) Number of persons
  2. 2) Incidence rate ratio
  3. 3) Confidence limit
  4. 4) P-value for trend among the IRRs for all 3 genotypes