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Table 2 Association of breast cancer with two additional polymorphisms selected from those detected by sequencing.

From: Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP

Polymorphism

N1cases

N1controls

IRR2(95% CI3)

P-trend4

RAI-3'd1

    

All ages

   

0.0008

   LL

38

59

1

 

   SL

127

165

1.39 (0.81–2.38)

 

   SS

200

150

2.44 (1.41–4.23)

 

<55 yr

   

0.01

   LL

5

15

1

 

   SL

18

25

1.46 (0.33–6.47)

 

   SS

33

14

6.29 (1.49–26.61)

 

55–60 yr

   

0.19

   LL

12

17

1

 

   SL

45

63

1.72 (0.63–4.73)

 

   SS

61

49

2.57 (0.88–7.48)

 

>60 yr

   

0.12

   LL

21

27

1

 

   SL

64

77

1.09 (0.52–2.60)

 

   SS

106

87

1.73 (0.83–3.64)

 

RAI -3'd2

    

All ages

   

0.005

   LL

149

113

1

 

   SL

168

199

0.62 (0.44–0.88)

 

   SS

66

88

0.50 (0.32–0.79)

 
  1. 1) Number of persons
  2. 2) Incidence rate ratio
  3. 3) Confidence limit
  4. 4) P-value for trend among the IRRs for all 3 genotypes