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Table 3 Sub-group analysis by sex and ethnicity (random-effects model)

From: Association between LRP5 polymorphism and bone mineral density: a Bayesian meta-analysis

Subgroup

Femoral neck BMD

Lumbar spine BMD

 

WMD (95% CI)

P value

I 2 (%)

WMD (95% CI)

P value

I 2 (%)

Overall

0.011 (0.004, 0.017)

0.002

46.8 (p = 0.05)

0.018 (0.012, 0.023)

<0.0001

0 (p = 0.55)

Ethnicity

      

Asian

0.011 (-0.006, 0.028)

0.21

51.3 (p = 0.13)

0.014 (0.002, 0.027)

0.02

0 (p = 0.62)

Caucasian

0.011 (0.003, 0.019)

0.01

52.1 (p = 0.05)

0.018 (0.012, 0.025)

<0.0001

10.5 (p = 0.35)

Gender

      

Men

0.011 (0.0004, 0.022)

0.04

50.6 (0.07)

0.014 (0.003, 0.025)

0.01

32.8 (p = 0.18)

Women

0.011 (0.001, 0.021)

0.03

55.8 (0.08)

0.020 (0.013, 0.028)

<0.0001

0 (p = 0.98)

  1. WMD, weighted mean difference in BMD between AA and AV/VV genotypes
  2. I 2, inconsistent index