Figure 2From: The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population Phylogeny of the MSH2 Met688Val and Ala848Ser variants. Multiple sequence alignment of the hMSH2 polypeptide sequence and orthologues from other species were generated using the ClustalW algorithm [31]. The following polypeptide sequences were used in the alignment: P43246 (Human; Homo sapiens), CAA57049 (Mouse; Mus musculus), S53609 (Frog; Xenopus laevis), XP 426110 (Chicken; Gallus gallus) and CAB42554 (Maize; Zea mays).Back to article page