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Table 2 Results of linkage analysis

From: Variation in WNT7A is unlikely to be a cause of familial Congenital Talipes Equinovarus

Position (cM)*

Recessive Model LOD

Incomplete penetrance LOD**

Non-parametric score

Non-parametric p-value

-0.5

-42.225244

-33.909119

0.50113

0.287155

-0.4

-44.768435

-35.992476

0.50248

0.286652

-0.3

-47.971668

-38.616184

0.50384

0.286191

-0.2

-52.351361

-42.183565

0.5052

0.285689

-0.1

-59.533471

-47.885138

0.50656

0.285229

0

- infinity

-72.191026

0.50793

0.284728

0.14

-69.148113

-48.627625

0.57235

0.262384

0.28

-65.288751

-46.023141

0.63682

0.241056

0.42

-64.988176

-45.483255

0.70133

0.220786

0.56

-67.984864

-46.804102

0.76591

0.201567

0.7

- infinity

-58.961596

0.83053

0.183456

0.71

-94.432148

-52.757392

0.8011

0.191547

0.72

-91.779782

-51.295166

0.77166

0.199903

0.74

-91.558237

-50.687057

0.74221

0.208489

0.75

-93.691707

-50.70706

0.71276

0.217304

0.76

- infinity

-54.960933

0.68331

0.226347

0.86

-53.997125

-38.450649

0.68135

0.226971

0.96

-47.61052

-34.138501

0.6794

0.227558

1.06

-43.628903

-31.376063

0.67746

0.228183

1.16

-40.69302

-29.317393

0.67553

0.228773

1.26

-38.353692

-27.6683

0.6736

0.229363

  1. * Positions in cM relative to D3S2403; D3S2385 and D3S1252 are at 0.7 and 0.76 cM respectively.
  2. ** Dominant model with penetrances of 0.33 for heterozygotes and homozygotes of disease allele.