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Table 1 Study Characteristics by Study Sample

From: Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies

  Framingham Heart Study ARIC whites
  Examination 7 Visit 1 Visit 4
Characteristic    
Sample size n 1007 11217 8717
Age, years 58.5 (9.6) 54.4 (5.7) 63.1 (5.6)
Male, % 49.1 47.2 46.3
Systolic blood pressure, mmHg 125 (18.5) 118.5 (17) 125.5 (18)
Antihypertensive medication, % 31.2 25.8 31.4
Diabetes mellitus, % 11.2 9.1 13.9
Body mass index, kg/m2 28.4 (5.8) 27.0 (4.9) 28.3 (5.2)
Current smokers, % 14.2 24.8 14.1
High density lipoprotein cholesterol, mg/dl 52.6 (16.1) 50.4 (16.8) 49.0 (16.3)
Serum creatinine, mg/dl 0.88 (0.28) 0.85 (0.20) 0.91 (0.24)
eGFR, ml/min/1.73 m2 86.6 (19.8) 89.6 (17.9) 80.5 (16.9)
Prevalent CKD*, n (%) 80 (8.0) 449 (4.0) 756 (8.7)
Incident CKD, n N/A N/A 843
Serum cystatin C, mg/l 0.96 (0.24) N/A N/A
  1. Data are presented as mean (standard deviation) for continuous and proportion for categorical variables for individuals with information on all characteristics available at FHS Offspring exam 7 and ARIC visits 1 and 4. *CKD was defined as eGFR <59 ml/min/1.73 m2 (women) and <64 ml/min/1.73 m2 (men). For definition of incident CKD and duration of follow-up see methods section. Abbreviations: eGFR: estimated glomerular filtration rate, CKD: chronic kidney disease.