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Table 1 Study Characteristics by Study Sample

From: Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies

 

Framingham Heart Study

ARIC whites

 

Examination 7

Visit 1

Visit 4

Characteristic

   

Sample size n

1007

11217

8717

Age, years

58.5 (9.6)

54.4 (5.7)

63.1 (5.6)

Male, %

49.1

47.2

46.3

Systolic blood pressure, mmHg

125 (18.5)

118.5 (17)

125.5 (18)

Antihypertensive medication, %

31.2

25.8

31.4

Diabetes mellitus, %

11.2

9.1

13.9

Body mass index, kg/m2

28.4 (5.8)

27.0 (4.9)

28.3 (5.2)

Current smokers, %

14.2

24.8

14.1

High density lipoprotein cholesterol, mg/dl

52.6 (16.1)

50.4 (16.8)

49.0 (16.3)

Serum creatinine, mg/dl

0.88 (0.28)

0.85 (0.20)

0.91 (0.24)

eGFR, ml/min/1.73 m2

86.6 (19.8)

89.6 (17.9)

80.5 (16.9)

Prevalent CKD*, n (%)

80 (8.0)

449 (4.0)

756 (8.7)

Incident CKD†, n

N/A

N/A

843

Serum cystatin C, mg/l

0.96 (0.24)

N/A

N/A

  1. Data are presented as mean (standard deviation) for continuous and proportion for categorical variables for individuals with information on all characteristics available at FHS Offspring exam 7 and ARIC visits 1 and 4. *CKD was defined as eGFR <59 ml/min/1.73 m2 (women) and <64 ml/min/1.73 m2 (men). †For definition of incident CKD and duration of follow-up see methods section. Abbreviations: eGFR: estimated glomerular filtration rate, CKD: chronic kidney disease.
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BMC Medical Genetics

ISSN: 1471-2350

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