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Table 2 Immunological evaluation of NDI patients

From: Immunological profile in a family with nephrogenic diabetes insipidus with a novel 11 kb deletion in AVPR2 and ARHGAP4 genes

  III-3
32 yr
III-4
29 yr
IV-4
5 yr
Normal range (adult) Normal range (children)
CD3+ [%] 74.3 68.9 85.9 55–78 55–83
CD4+/CD3+ [%] 54.9 17.7 69.6 28–57 27–53
CD8+/CD3+ [%] 34.5 61.8 14 10–39 19–34
CD4/CD8 1.6 0.3 5 1.0–3.6 0.9–2.6
CD19+ [%] 5.2 5.7 6.7 6–19 10–31
IgG (mg/dl) 810.0 741.0 754.0 870–1700 600–1450
IgA (mg/dl) 147.0 72.0 105.0 110–410 39–233
IgM (mg/dl) 59.0 127.0 72.0 33–190 69–268
TREC/μgDNA 1.9 × 102 2.8 × 102 1.6 × 103 3.4 ± 3.6 × 102 3.5 ± 2.8 × 103
  1. The normal range of the lymphocyte subpopulation was lower and the upper confidence limit at a confidence level of 0.95. The normal range of IgG, IgA, and IgM are calculated as mean - 2SD (lower) and mean + 2SD (upper). The normal range of TREC is expressed as mean ± SD.