Distribution of the FYB ES and RHCE*ce(733C>G) alleles in an Argentinean population: Implications for transfusion medicine

Table 3 Serologic and molecular study of the Rh system

Phenotype	HRB^a	C733	G733	Genotype^b	N° of individuals (total = 206)	Frequency
DCcee	+	+	-	DCe/dce	69	0.3350
	+	+	-	Dce/dCe	1	0.0049
	-	+	-	DCe/Dce	4	0.0194
	-	+	+	DCe/Dce(733C>G)	2	0.0097
DCCee	-	+	-	DCe/DCe	28	0.1359
	+	+	-	DCe/dCe	1	0.0049
DCcEe	-	+	-	DCe/DcE	26	0.1262
	+	+	-	DCE/dce	1	0.0049
	+	+	-	DcE/dCe	1	0.0049
DccEe	+	+	-	DcE/dce	17	0.0825
	+	+	-	Dce/dcE	1	0.0049
	-	+	-	DcE/Dce	3	0.0146
	-	+	+	DcE/Dce(733C>G)	3	0.0146
DccEE	-	+	-	DcE/DcE	10	0.0485
Dccee	+	+	-	Dce/dce	5	0.0243
	+	+	+	Dce(733C>G)/dce	3	0.0146
	-	+	+	Dce/Dce(733C>G)	1	0.0049
DCcEE	-	+	-	DcE/DCE	1	0.0049
DCCEe	-	+	-	DCe/DCE	1	0.0049
dccee	+	+	-	dce/dce	25	0.1214
dCcee	+	+	-	dCe/dce	3	0.0146

a. HRB = Hybrid Rhesus box. "+" means "presence" while "-" means "abscence".
b. RH haplotypes in the different Rh phenotypes were determined considering the CcEe phenotype, the RHD zygosity determined by PCR and the segregation analysis of the Rh antigens in each trio. In those cases in which different combinations of haplotypes could be assigned to a given sample, the combination requiring the least number of infrequent haplotypes in both parents was chosen as the most plausible explanation.

ISSN: 1471-2350