Table 1 Clinical characteristics of samples used in this study
From: Genetic and functional association of FAM5C with myocardial infarction
Variable | eoCAD Probands | ACS Probands | MI Cases | Controls | Aorta Samples |
|---|---|---|---|---|---|
| Â | (n = 422) | (n = 228) | (n = 368) | (n = 289) | (n = 88) |
Age of onset (SD) | 44.2 (5.8) | 43.9 (6.1)†| 51.5 (10.2)†| 69.0 (7.0) exam | 37.8 (13.2) |
Race: Caucasian | 92.9% | 93%†| 100%†| 100.0% | 87.9% |
African American | 2.1% | 2.2% | 0.0% | 0.0% | 8.6% |
American Indian | 4.0% | 3.0% | 0.0% | 0.0% | 0.0% |
Asian | 0.7% | 0.9% | 0.0% | 0.0% | 2.0% |
Hispanic | 0.0% | 0.0% | 0.0% | 0.0% | 3.5% |
Other (unknown) | 0.2% | 0.4% | 0.0% | 0.0% | 0.0% |
Sex: Male | 70.6% | 72%†| 83%†| 43.0% | 55.2% |
Family history of CAD | 100.0% | 100%†| 58%†| 28.0% |  |
Body Mass Index (SD) | 29.9 (5.8) | 29.9 (6.3) | 29.9 (6.8) | 28.2 (6.5) | Â |
Smoking | 78.0% | 84.0%†| 72%†| 39.0% |  |
Diabetes | 22.3% | 22.0% | 29.0% | 15.0% | Â |
Hypertension | 56.9% | 57%†| 66%†| 66.0% |  |
MI | 65.9%* | 89.0%*†| 100%†| 0.0% | Data not available |
Sys/Dias BP (SD) | 140.1/84.0* (21.5/11.4) | 140.6†/87.0* (22.0/12.0) | 138.0†/74.0 (24.0/12.0) | 149.0/76.0 (23.0/13.0) |  |
Total Cholesterol (SD) | 239.1 (64.8) | 235.0†(67.0) | 189.0†(56.0) | 189.0 (43.0) |  |
LDL (SD) | 146.1 (54.3) | 161.0†(125.0) | 108†(42.0) | 105.0 (35.0) |  |
HDL (SD) | 38.67 (16.3) | 40.0 (14.0) | 39.0 (12.0) | 51.0 (19.0) | Â |
Triglycerides (SD) | 230.1 (138.8) | 221.0 (157.0) | 226.0 (239.0) | 169.0 (133.0) | Â |