Figure 2
From: Genetic and functional association of FAM5C with myocardial infarction
FAM5C tagSNPs are associated and linked to acute coronary syndrome. 47 haplotype tagging SNPs were selected to span the length of FAM5C as well as 15 kb up and 5 kb downstream of the gene to account for potential regulatory elements. Parametric linkage (A), APL association (B) and PDT association (C) were assessed. SNPs that were linked (LOD ≥ 1) and/or associated (p ≤ 0.05) were selected for replication (markers that fall above the dashed lines, n = 16). * denotes rs10920501.