Table 2 Results on selected chromosome intervals after increment in marker density. Position (cM) refers to the genetic position of the maximum LOD score, while Position (bp) refers to the physical position given in build 36.1 of the genome (NCBI)
From: Genetic loci linked to Type 1 Diabetes and Multiple Sclerosis families in Sardinia
Scan | Chromosome | Position(cM) | Position(bp) | Closest Marker | LOD | P Value | λs | CI | % Information_Content |
|---|---|---|---|---|---|---|---|---|---|
T1D_SCAN | 1p31.1 | 109.43 | 82315937 | D1S207 | 1.5 | 4.0 × 10-3 | 1.31 | 0.90 – 1.92 | 89 |
|  | 10q21.1 | 77.943 | 61136296 | D10S589 | 2.1 | 1.0 × 10-3 | 1.84 | 1.16 – 2.92 | 79 |
|  | 22q11.21 | 10.38 | 20349111 | D22S446 | 1.5 | 4.0 × 10-3 | 1.53 | 1.01 – 2.32 | 89 |
MS_SCAN | 1q42.2 | 240.84 | 229780888 | D1S251 | 2.5 | 4.0 × 10-4 | 4.03 | 1.44 – 11.3 | 93 |
|  | 18p11.22 | 37.767 | 10732702 | D18S1158 | 2.6 | 3.0 × 10-4 | 4.27 | 1.48 – 12.32 | 70 |
|  | 20p12.3 | 15.43 | 6090696 | D20S194 | 1.6 | 3.0 × 10-3 | 2.13 | 1.03 – 4.40 | 83 |
T1D-MS_SCAN | 10q21.1 | 78.52 | 61136296 | D10S589 | 2.3 | 6.0 × 10-4 | 1.58 | 1.13 – 2.24 | 83 |
|  | 20p12.3 | 15.43 | 6090696 | D20S194 | 2.5 | 4.0 × 10-4 | 1.77 | 1.22 – 2.56 | 81 |
|  | 22q11.21 | 10.38 | 20349111 | D22S446 | 0.9 | 2.0 × 10-2 | 1.26 | 0.93 – 1.70 | 90 |