Skip to main content

Table 1 Results of non-parametric linkage analysis on the whole genome implemented using Merlin software. Position (cM) refers to the genetic position of the maximum LOD score, while Position (bp) refers to the physical position given in build 36.1 of the genome (NCBI)

From: Genetic loci linked to Type 1 Diabetes and Multiple Sclerosis families in Sardinia

Scan Chromosome Position(cM) Position(bp) Closest Marker LOD P Value λs CI % Information_Content
T1D_SCAN 1p31.1 109.48 82315937 D1S207 1.7 3.0 × 10-3 1.35 0.91 – 1.99 79
  6p21.32 (HLA) 40.48 32734820 D6S2447 8.3 < 1.0 × 10-5 2.81 1.56 – 5.07 71
  6q26 160.77 162759585 D6S1599 1.1 1.1 × 10-2 1.46 0.97 – 2.19 77
  10q21.2 78.64 64077501 D10S1652 1.1 1.3 × 10-2 1.33 0.89 – 2.00 70
  22q11.22 10.38 20587780 D22S539 1.5 4.0 × 10-3 1.89 1.05 – 2.57 66
MS_SCAN 1q42.2 246.27 232524978 D1S2800 1 2.0 × 10-2 2.23 1.06 – 4.70 61
  18p11.21 41.24 11482730 D18S53 1.6 3.0 × 10-3 3.2 1.28 – 7.99 64
  20p12.3 18.32 7607867 D20S115 1.1 1.3 × 10-2 1.8 0.93 – 3.47 76
T1D-MS_SCAN 6p21.32 (HLA) 39.65 32734723 D6S2447 5.1 < 1.0 × 10-5 1.65 1.15 – 2.34 69
  6q26 157.21 162115167 D6S305 1.2 9.0 × 10-3 1.25 0.93 – 1.69 79
  10q21.2 82.093 64077501 D10S1652 1.4 6.0 × 10-3 1.33 0.96 – 1.84 63
  20p12.3 18.32 7607867 D20S115 1.2 1.0 × 10-2 1.39 1.00 – 1.93 71
  22q11.22 10.38 20587780 D22S539 1.3 8.0 × 10-3 1.51 1.07 – 2.13 65