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Figure 3 | BMC Medical Genetics

Figure 3

From: Ser80Ile mutation and a concurrent Pro25Leu variant of the VHL gene in an extended Hungarian von Hippel-Lindau family

Figure 3

Three-dimensional computational modeling of the Ser80 and Ile80 residues using CPK diagram (upper part) and schematic representation of hydrogen-bonds between residues Gly104 and Asn78, between Arg79 and Ile151, between Ser80 and Ile151, beween Ser80 and Pro103, between Ser80 and Leu153, and between Pro103 and Arg82 in wild type pVHL and the consequences of the Ser to Ile change at amino acid position 80 (lower part). All figures were generated with Swiss-PdbViewer in combination with POV-Ray.

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BMC Medical Genetics

ISSN: 1471-2350

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