Skip to main content

Table 2 SNPs in the LOX-1 gene that were genotyped in ADVANCE subjects

From: Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

SNP Name dbSNP Type Change Minor/Major Allele Minor Allele Freq (%)
      White/European Black/African American East Asian Hispanic
LOX1.1 rs2742112 5' 391 5' transc start A/G 31 46 57 39
LOX1.2 rs11053646 exon mRNA 563, Lys-Asn C/G 9 20 16 6
LOX1.3 rs3736232 intron 26 3' exon 4 C/G 49 20 23 49
LOX1.16 rs1050286 exon 3' UTR G/A 49 23 23 50
  1. Bold indicates non-synonymous amino acid change. For association analysis, the minor allele is defined as the least prevalent allele across both sets of controls in all race/ethnic groups combined.