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Table 2 SNPs in the LOX-1 gene that were genotyped in ADVANCE subjects

From: Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

SNP Name

dbSNP

Type

Change

Minor/Major Allele

Minor Allele Freq (%)

     

White/European

Black/African American

East Asian

Hispanic

LOX1.1

rs2742112

5'

391 5' transc start

A/G

31

46

57

39

LOX1.2

rs11053646

exon

mRNA 563, Lys-Asn

C/G

9

20

16

6

LOX1.3

rs3736232

intron

26 3' exon 4

C/G

49

20

23

49

LOX1.16

rs1050286

exon

3' UTR

G/A

49

23

23

50

  1. Bold indicates non-synonymous amino acid change. For association analysis, the minor allele is defined as the least prevalent allele across both sets of controls in all race/ethnic groups combined.