Skip to main content

Table 6 Number of tag SNPs/total SNPs with MAF ≥ 3% (ratio) in each of five populations using LDSelect with NHLBI resequencing data. The last column shows number of tag SNPs and total SNPs combined across the five populations using multiPopTagSelect.

From: SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis

Gene

European N = 47

Hipanic N = 48

Chinese N = 47

African American N = 24

Yoruban N = 24

Multiple

ACO1

26/58 (0.45)

29/56 (0.52)

28/57 (0.49)

69/111 (0.62)

65/110 (0.59)

97/145 (0.67)

CYBRD1

15/62 (0.24)

20/58 (0.34)

17/62 (0.27)

28/57 (0.49)

34/65 (0.52)

46/85 (0.54)

FLVCR

17/99 (0.17)

11/75 (0.15)

8/83 (0.10)

18/82 (0.22)

18/91 (0.20)

27/114 (0.24)

FTH1

5/13 (0.38)

10/17 (0.59)

4/7 (0.57)

11/19 (0.58)

8/14 (0.57)

17/27 (0.63)

HAMP

4/7 (0.57)

4/7 (0.57)

7/10 (0.70)

8/10 (0.80)

9/11 (0.82)

11/15 (0.73)

HCP1

3/6 (0.50)

5/9 (0.56)

4/9 (0.44)

11/16 (0.69)

11/15 (0.73)

17/22 (0.77)

HEPH

13/38 (0.34)

10/36 (0.28)

9/10 (0.90)

16/58 (0.28)

21/53 (0.40)

49/95 (0.52)

HFE2

5/7 (0.71)

5/8 (0.63)

4/7 (0.57)

8/10 (0.80)

5/7 (0.71)

10/13 (0.77)

IREB2

11/52 (0.21)

11/47 (0.23)

15/63 (0.24)

21/94 (0.22)

18/95 (0.19)

42/134 (0.31)

PGRM1

5/10 (0.50)

2/2 (1.00)

0/0

8/11 (0.73)

10/13 (0.77)

15/19 (0.79)

PGRM2

2/4 (0.50)

4/8 (0.50)

7/9 (0.78)

10/13 (0.77)

11/17 (0.65)

16/22 (0.73)

TF

20/44 (0.45)

24/50 (0.48)

17/49 (0.35)

34/61 (0.56)

42/61 (0.69)

61/87 (0.70)

TFR2

4/6 (0.67)

3/5 (0.60)

5/7 (0.71)

5/5 (1.00)

6/7 (0.86)

8/9 (0.89)

TFRC

36/119 (0.30)

34/115 (0.30)

22/93 (0.24)

43/135 (0.32)

44/110 (0.40)

87/187 (0.47)

Av No. tags

11.9

12.3

10.5

20.7

21.6

35.9