Table 3 Effect of varying r2 on number of tagSNPs selected using Tagger and MAF≥3% for six genes using NHLBI resequencing data. First number is tagSNPs using 2 and 3 multi-marker SNP tagging, second number is number of tests (the number of unique combinations of tag SNPs required to represent all SNPs).
From: SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis
r2 | TF | CYBRD1 | ACO1 | FLVCR | IREB2 | TFRC |
|---|---|---|---|---|---|---|
0.50 | 10/10 | 9/9 | 19/21 | 8/8 | 10/11 | 22/22 |
0.55 | 10/10 | 10/10 | 20/21 | 9/9 | 11/11 | 22/22 |
0.60 | 11/11 | 12/14 | 21/23 | 10/10 | 11/11 | 25/25 |
0.65 | 12/13 | 14/16 | 22/23 | 10/11 | 11/11 | 26/26 |
0.70 | 14/16 | 15/15 | 22/23 | 11/12 | 11/11 | 27/28 |
0.75 | 16/18 | 15/15 | 23/25 | 13/14 | 12/12 | 29/29 |
0.80 | 17/19 | 15/15 | 23/26 | 15/17 | 12/12 | 33/36 |
0.85 | 19/20 | 16/16 | 26/27 | 16/18 | 12/12 | 37/38 |
0.90 | 19/21 | 18/21 | 27/32 | 17/18 | 12/12 | 42/43 |
0.95 | 22/23 | 21/25 | 31/35 | 19/20 | 13/13 | 46/51 |
1.00 | 23/36 | 21/25 | 34/37 | 22/27 | 14/15 | 50/52 |