Table 3 Histamine receptor polymorphisms according to gender and age of onset of PD. PD patients were subdivided in groups according to age of onset (under or over the median age) and according to gender.
From: Genetic variability of histamine receptors in patients with Parkinson's disease
PD PATIENTS H1 SER N (OR; 95 C.I.) [Χ2; P VALUE] | PD PATIENTS H2 – 1018 A N (OR; 95 C.I.) [Χ2; P VALUE] | CONTROL SUBJECTS H2 – 1018 A N | |
|---|---|---|---|
Overall patients | 2 (2.19 a; 0.74–2.19) [2.37,0.123] | 14 (0.71; 0.37–1.39) [0.98, 0.322] | 23 |
Men | 0, (--) | 3 (0.28; 0.08–0.95) [4.17,0.041] | 12 |
Women | 2 (2.19 a; 0.74–2.20) [2.37,0.123] | 11 (1.20; 0.52–2.76) [0.16, 0.681] | 11 |
Onset under 68 yr | 0, (--) | 6 (0.58; 0.24–1.42) [1.36, 0.244] | N.A. |
Onset over 68 yr | 2 (3.45 a; 1.19–3.48) (4.92;0.027) | 8 (0.85; 0.38–1.90) [0.154, 0.695] | N.A. |