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Table 2 Allele and genotype frequency distribution among AMI cases and controls.

From: Role of TGF-β1 haplotypes in the occurrence of myocardial infarction in young Italian patients

Polymorphism

Genotype

Cases (%)

Controls (%)

P value

Crude ORs (95%CI)

P value

Adjusted ORs (95%CI)

P value

G-800A

GG

175 (87.1)

168 (83.6)

a0.571

1

 

1

 
 

AG

25 (12.4)

31 (15.4)

 

0.774 (0.439–1.366)

0.377

0.645 (0.225–1.849)

0.414

 

AA

1 (0.5)

2 (1.0)

 

0.48 (0.043–5.343)

0.551

0.177 (0.002–2.721)

0.427

 

G/A

375/27

367/35

b0.290

    

C-509T

CC

67 (33.3)

80 (39.8)

a0.062

1

   
 

CT

87 (43.3)

92 (45.8)

 

1.129 (0.729–1.749)

0.586

1.365 (0.604–3.083)

0.454

 

TT

47 (23.4)

29 (14.4)

 

1.935 (1.100–3.406)

0.022

1.943 (0.754–5.003)

0.169

 

C/T

221/181

252/150

b0.026

    

Leu10Pro

TT

55 (27.4)

69 (34.3)

a0.005

1

   
 

CT

88 (43.8)

101 (50.2)

 

1.093 (0.693–1.723)

0.702

1.138 (0.481–2.693)

0.768

 

CC

58 (28.9)

31 (15.4)

 

2.347 (1.338–4.117)

0.003

1.589 (0.610–4.136)

0.343

 

T/C

198/204

239/163

b0.004

    
  1. a Pearson chi square P value of the 3 × 2 contingency table; b Pearson chi square P value of the 2 × 2 contingency table. Crude and adjusted odds ratios (for smoking habits, family history, hypercholesterolemia and hypertension) and 95% CI are reported.