Table 2 Ontario Ministry of Health and Long-Term Care (MOHLTC) criteria for BRCA1 and BRCA2 genetic testing eligibility
From: Selecting a BRCA risk assessment model for use in a familial cancer clinic
Non-Ashkenazi Jewish | Ashkenazi Jewish |
|---|---|
• Breast cancer <35 years | • Breast cancer <50 years |
• Male breast cancer | • Breast cancer at any age with family history |
• Serous ovarian cancer | • Unaffected individual with family history |
• Breast cancer <60 years and family history of ovarian or male breast cancer |  |
• Breast and ovarian cancer in same individual |  |
• Bilateral breast cancer |  |
• 2 cases breast cancer <50 years |  |
• 2 cases ovarian cancer |  |
• 3 cases breast cancer any age |  |
• Known mutation |  |
• Clinical judgment |  |