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Table 1 Genotype and allele frequencies of SNPs from the IL10 gene cluster in MDD patients (n = 153) and control individuals (n = 277)

From: Polymorphisms in the interleukin-10 gene cluster are possibly involved in the increased risk for major depressive disorder

 

Alleles

 

Genotypes

 

Alleles

 

SNP ID

1/2*

Groups

11

12

22

P-value

1

2

P-value

rs1800872

C/A

Controls

51.0

41.3

7.7

0.5460

71.6

28.4

0.5238

  

Patients

53.2

41.0

5.8

 

73.7

26.3

 

rs2243188

C/A

Controls

65.8

30.7

3.5

0.1790

81.1

18.9

0.1820

  

Patients

57.1

40.0

2.9

 

77.1

22.9

 

rs2243193

G/A

Controls

62.8

33.1

4.1

0.4803

79.3

20.7

0.4636

  

Patients

59.2

35.9

4.9

 

77.1

22.9

 

rs2981572

T/G

Controls

48.4

42.9

8.7

0.6789

69.9

30.1

0.6406

  

Patients

46.4

43.6

10.0

 

68.2

31.8

 

rs1518108

C/T

Controls

27.5

56.6

15.9

0.8755

55.8

44.2

0.8251

  

Patients

29.5

51.1

19.4

 

55.0

45.0

 

rs1150253

G/A

Controls

27.1

55.2

17.7

0.8855

54.7

45.3

0.8657

  

Patients

31.9

46.8

21.3

 

55.3

44.7

 

rs1150258

T/C

Controls

27.0

56.4

16.6

0.8741

55.2

44.8

0.8227

  

Patients

29.9

48.9

21.2

 

54.4

45.6

 
  1. * 1 represents the major allele, 2 represents the minor allele