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Table 4 Association study with Ngb haplotypes in LVD and SVD patients

From: Association between Ngb polymorphisms and ischemic stroke in the Southern Chinese Han population

Haplotype Poly1/Poly2

LVD vs Control

 

SVD vs Control

 
 

LVD

n (%)

Control

n (%)

OR (95%CI)

P

SVD

n (%)

Control

n (%)

OR (95%CI)

P

c-6a

131.91(29.8)

62.48(19.8)

1.726(1.224–2.434)

0.002

64.59(24.1)

62.48(19.8)

1.288(0.869–1.910)

0.201

c-5a

149.09(33.7)

68.52(21.7)

1.838(1.318–2.563)

<0.0001

95.42(35.6)

68.52(21.7)

1.997(1.384–2.880)

<0.0001

t-6a

92.09(20.8)

103.53(32.8)

0.540(0.389–0.750)

<0.0001

62.42(23.3)

103.53(32.8)

0.623(0.431–0.900)

0.011

t-5a

68.91(15.6)

81.47(25.8)

0.532(0.371–-0.762)

0.001

45.58(17.0)

81.47(25.8)

0.590(0.393–0.886)

0.010

Global χ2

   

36.407

   

20.966

Fisher P

   

<0.0001

   

<0.0001

  1. Poly1: 89+104 c>t; Poly2: 322-110 (6a)>5a