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Table 5 Performance of two predictive models in assessment T2D risk

From: TCF7L2variant genotypes and type 2 diabetes risk in Brazil: significant association, but not a significant tool for risk stratification in the general population

Model 1 – Only Demography variables

Cutoffs Values

Sensitivity

Specificity

PPV

NPV

Accuracy

OR (95%CI)

P value

Needing to Additional Tests(%)

16.5

0.8426

0.6071

0.19

0.972

0.63

8.27 (3.86–12.68)

< 0.00001

43.7

18

0.7037

0.7162

0.213

0.957

0.71

5.99 (3.38–8.60)

< 0.00001

32.51

Model 2 – Demography and TCF7L2 TT Genotype variables

Cutoffs Values

        

16.5

0.8426

0.5939

0.185

0.972

0.62

7.83 (3.66–12.0)

< 0.00001

44.89

18

0.7222

0.7081

0.213

0.959

0.71

6.30 (3.51–9.1)

< 0.00001

33.42