Table 3 Overview of the results for the exon 45–55 multiexon skipping experiments in deletion exon 48–50 cell cultures
From: Assessment of the feasibility of exon 45–55 multiexon skipping for duchenne muscular dystrophy
Used AONs | Exon 45–55 skip | NT | Other skips | NT |
|---|---|---|---|---|
Exon 45 & 55 (mix) | 2/6 | 3/6 | Exon 45–52 skip (1×) | Exon 45–53 skip (2×) |
Exon 45 & 55 (linked) | 2/6 | 2/6 | Exon 45–53 & 55 skip (1×) | |
3/6 | 4/6 | |||
Exon 45, 46, 47, 48, 49, 50, 51, 52, 53, 54 & 55 | 0/6 | 2/6 | Exon 45–53 skip (1×) | Exon 45–53 & 55 skip (1×) |
2/6 | 3/6 | Exon 45–53 & 55 skip (1×) |