Table 1 Major QTL findings per chromosome, LOD > 1.7 in African Americans
No | Rotation | Excluding DM | Chromosome | Sex-averaged distance in cM, peak and (surrounding markers) | Marker name | Dname | LOD* Score | Factor Domain |
|---|---|---|---|---|---|---|---|---|
1 | NO | NO | 2 | 68.76 (64.29–73.61) | ATA4F03-ATA27D04 | D2S1356-D2S1352 | 2.84 | BMI-INS |
2 |  |  | 12 | 100.42 (95.03–104.12) | GATA63D12-GATA85A04 | D12S1064-D12S1300 | 1.98 | BMI-INS |
3 | Â | Â | 19 | 68.84 (68.08) | MDF139 | D19S178 | 2.67 | BP |
4 | Â | Â | 20 | 4.13 (2.13) | AFM077XD3 | D20S103 | 1.78 | BMI-INS |
5 | NO | YES | 2 | 49.76 (47.97–55.51) | GATA8F07-GATA86E02 | D2S405-D2S1788 | 2.41 | BMI-INS |
6 |  |  | 2 | 65.76 (64.29–73.61) | ATA4F03-ATA27D04 | D2S1356-D2S1352 | 3.62 | BMI-INS |
7 | Â | Â | 5 | 114 (114.75) | ATA4D10 | D5S1453 | 2.36 | BP |
8 |  |  | 11 | 91.11 (85.48–100.82) | GATA30G01-GATA28D01 | D11S2002-D11S2000 | 1.80 | BMI-INS |
9 |  |  | 12 | 91.42 (83.19–95.03) | GATA26D02-GATA63D12 | D12S1052-D12S1064 | 3.22 | BMI-INS |
10 | Â | Â | 18 | 54.84 (54.40) | GATA64H04 | D18S877 | 2.37 | BMI-INS |
11 |  |  | 19 | 70.84 (68.08–78.08) | MFD139-MFD232 | D19S178-D19S246 | 2.18 | BP |
12 | VAR†| NO | 5 | 36.00 (36.25) | GATA134B03 | D5S2845 | 2.42 | LIPIDS-INS |
13 |  |  | 10 | 153.32 (148.17–165.27) | GGAA5D10-GGAA23C05 | D10S1213-D10S1248 | 1.87 | LIPIDS-INS |
14 | Â | Â | 11 | 113.11 (113.13) | GATA23606 | D11S1998 | 2.66 | LIPIDS-INS |
15 | Â | Â | 19 | 67.84 (68.08) | MFD139 | D19S178 | 2.97 | BP |
16 | VAR | YES | 2 | 64.76 (64.29) | ATA4F03 | D2S1356 | 3.90 | BMI-INS |
17 | Â | Â | 5 | 115.00 (115.75) | ATA4D10 | D5S1453 | 2.02 | BP |
18 |  |  | 12 | 91.42 (83.19–95.03) | GATA26D02-GATA63D12 | D12S1052-D12S1064 | 3.34 | BMI-INS |
19 | Â | Â | 18 | 54.84 (54.40) | GATA64H04 | D18S877 | 2.02 | BMI-INS |
20 | Â | Â | 19 | 68.84 (68.08) | MFD139 | D19S178 | 1.98 | BP |