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Table 2 Proportion of association results at different p-value thresholds

From: Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study

 

QT

RR

PR

LF/HF

Tot Power

SDNN

Average

p < 0.0001

0.000127

0.000197

0.000169

0.000281

0.000197

0.000112

0.000180

p < 0.001

0.00165

0.00149

0.00156

0.00143

0.00172

0.00145

0.00155

p > 0.10

0.891

0.886

0.882

0.895

0.895

0.893

0.890

  1. Shown are the proportion of p-values for single SNP association tests using GEE which are more extreme than 0.0001, 0.001 and less extreme than 0.10 for the six electrocardiographic and heart rate variability traits, after excluding SNPs with call rate <80%, minor allele frequency <10%, Hardy-Weinberg equilibrium p-value < 0.001. The proportions observed closely approximate the proportions expected for a null distribution – 0.0001, 0.001 and 0.90.