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Table 4 Top Results for Geometric Means of SBP and DBP Considered Jointly (at examinations 1, 7 and in the long term), and arterial stiffness phenotypes considered jointly.

From: Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness

SNP Exam Chr. Position P value Gene
DBP and SBP
rs10493340 1 1 63,303,150 1.49 × 10-5  
rs9321764 7 6 140,532,157 2.89 × 10-5  
rs10491334 7 5 110,800,303 3.74 × 10-5 CAMK4
rs2121070 1 14 75,720,517 3.96 × 10-5 C14orf118
rs1328925 1 4 159,547,895 4.22 × 10-5 TMEM144
rs10510079 1 10 122,473,101 7.27 × 10-5  
rs7562854 7 2 12,149,816 7.52 × 10-5  
rs1841055 7 4 70,039,785 7.63 × 10-5 UGT2A3
rs10485320 7 6 47,884,860 7.75 × 10-5 OPN5
rs9298203 7 8 73,270,276 8.28 × 10-5  
Arterial stiffness
rs10518082 7 4 72,282,885 0.002 DCK
rs1322512 7 6 153,040,067 0.005 SYNE1
rs10511389 7 3 120,557,547 0.007 CDGAP
rs883524 7 8 23,250,536 0.008 LOXL2
rs965674 7 5 82,518,340 0.008 XRCC4
rs10502173 7 11 112,708,233 0.009 TTC12
rs1468512 7 17 64,731,363 0.010 ABCA10
rs4075701 7 2 116,146,020 0.011  
rs10496604 7 2 123,501,987 0.011  
rs770189 7 5 88,124,195 0.011 MEF2C
  1. Based on Additive genetic effects model using GEE and minor allele frequency of 0.1, call rate >= 0.80 and HWE p value >= 0.001
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