From: Genome-wide association with bone mass and geometry in the Framingham Heart Study
Trait | Abbreviation | Gender (N) | Cohort, exam cycle | Adjustment* |
---|---|---|---|---|
Bone mineral density (BMD) | ||||
Femoral BMD** | FNBMD | Combined (1141) | Original, ex. 22–24, Offspring, ex. 6–7 | 1) multivariable-adjusted residuals (age, age^{2}, height, BMI, smoking, physical activity, estrogen therapy) |
FNBMDf | Females (646) | |||
FNBMDm | Males (495) | |||
Trochanter BMD** | TRBMD | Same as above | Same as above | Same as above |
TRBMDf | ||||
TRBMDm | ||||
Lumbar spine BMD** | LSBMD | Combined (1117) | Same as above | Same as above |
LSBMDf | Females (641) | |||
LSBMDm | Males (486) | |||
Quantitative ultrasound (QUS) | ||||
Broadband ultrasound attenuation** | BUA | Combined (1105) | Original, ex. 24, Offspring, ex. 6–7 | 1) multivariable-adjusted residuals (age, age^{2}, height, BMI, smoking, physical activity, estrogen therapy) |
Speed of Sound | SOS | Combined (1104) | Same as above | Same as above |
Hip geometry | ||||
Neck-shaft angle** | NSA1 | Combined (1096) | Original, ex. 22–24, Offspring, ex. 6–7 |
1) age, age^{2} 2) multivariable-adjusted ranked residuals (age, age^{2}, height, BMI) |
NSAf | Females (622) | |||
NSAm | Males (474) | |||
Femoral neck length** | NeckLeng1 | Combined (1090) | Same as above | Same as above |
NeckLengf | Females (619) | |||
NeckLengm | Males (471) | |||
Neck width** | NeckW1r | Combined (1095) | Same as above | Same as above |
NeckW1rf | Females (618) | |||
NeckW1rm | Males (477) | |||
Neck section modulus** | NeckZ1r | Combined (1096) | Same as above | Same as above |
NeckZ1rf | Females (618) | |||
NeckZ1rm | Males (478) | |||
Neck Cross-Sectional Moment of Inertia | NeckCSMI1r | Combined (1094) | Same as above | Same as above |
NeckCSMI1rf | Females (618) | |||
NeckCSMI1rm | Males (476) | |||
Neck Average Buckling Ratio | NeckAvgBR1r | Combined (1096) | Same as above | Same as above |
NeckAvgBR1rf | Females (618) | |||
NeckAvgBR1rm | Males (478) | |||
Shaft width** | ShaftW1 | Combined (1028) | Same as above | Same as above |
ShaftW1f | Females (599) | |||
ShaftW1m | Males (429) | |||
Shaft Section modulus** | ShaftZ1r | Combined (1028) | Same as above | Same as above |
ShaftZ1rf | Females (599) | |||
ShaftZ1rm | Males (429) | |||
Shaft Cross-Sectional Moment of Inertia | ShaftCSMIr | Combined (1026) | Same as above | Same as above |
ShaftCSMIrf | Females (599) | |||
ShaftCSMIrm | Males (427) | |||
Shaft Average Buckling Ratio | ShaftAvgBR1r | Combined (1028) | Same as above | Same as above |
ShaftAvgBR1rf | Females (599) | |||
ShaftAvgBR1rm | Males (429) | |||
Inter-Trochanteric Average Buckling Ratio | ITAvgBR1r | Combined (1024) | Same as above | Same as above |
ITAvgBR1rf | Females (596) | |||
ITAvgBR1rm | Males (428) |