Table 2 Genotype distribution and allele frequency of the G1522A variant in the SMPD1 gene in control and low HDL-cholesterol subjects.
Genotype or allele | Control subjects (n) | Low HDL-cholesterol subjects (n) | χ2, two-sided p-value and O.R. |
|---|---|---|---|
GG | 56.1% (129) | 64.1% (75) | 0.152† |
AG | 38.3% (88) | 29.1% (34) | 0.72 (0.45–1.13)‡ |
AA | 5.6% (13) | 6.8% (8) | |
G | 75.2% | 78.6% | 0.317 |
A | 24.8% | 21.4% | 0.82 (0.57–1.20)‡ |