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Table 1 The clinical parameters of stroke and control groups.

From: The intron 4c allele of the NOS3 gene is associated with ischemic stroke in African Americans

 

Control group (n = 502)

Case group (n = 377)

Age (yrs)

65.32 ± 14.83

69.92 ± 13.52 †

Gender (male, %)

41.2%

48.3%*

Hypertension (%)

55.1%

76.0%†

Diabetes (%)

24.6%

37.4%†

Ex-smoker/Current smoker (%)

8.6%/17.7%

8.7%/17.9%

Race (Caucasian/African American/Asian-Indian/Hispanic/Asian-oriental/Others) (%)

 

81.7%/8.4%/3.0%/3.8%/0.8%/2.4%)

68.4%/11.9%/5.8%/6.9%/4.0%/2.9%)†

TOAST classification

  

   Cardioembolism

NA

24.1%

   Large artery atherosclerosis

NA

31.8%

   Small vessel occlusion

NA

24.1%

   Others / unknown

NA

19.9%

Glu298Asp allele distribution G/T (2n)

482/198

460/194

Intron 4 VNTR allele distribution a/b/c (2n)

164/830/4

127/590/15†

   Caucasian

126/688/2

87/410/3

   African American

23/57/2

20/57/11*

   Asian-Indian

3/27/0

7/36/1

   Hispanic

5/33/0

9/41/0

   Asian-Oriental

2/6/0

1/27/0

   Others

5/19/0

3/19/0

  1. *p < 0.05, †p < 0.01, the clinical data were expressed as mean ± SD where appropriate.
  2. NA = not applicable