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Table 4 Results of haplotype association analysis

From: Association of autism with polymorphisms in the paired-like homeodomain transcription factor 1 (PITX1) on chromosome 5q31: a candidate gene analysis

SNPs ID

Alleles

Freq.

Z-score

P-value3 (P corrected )

Relative Risk

rs479632 – rs1131611 – rs888685 – rs3805663

C-G-T-A

0.64

2.000

0.0455 (0.0703)

 
 

G-G-A-G

0.24

-0.267

0.7894

 
 

C-T-A-G

0.11

-2.249

0.0245 (0.0416)

 

rs6872664 – rs6596188

C-A

0.88

2.636

0.0084 (0.0178)

RRHT = 1.46 [1.13; 1.88]

RRHO = 2.12 [1.27; 3.54]

 

T-T

0.12

-2.636

0.0084 (0.0178)

 

rs11959298 – rs6596189

A-C

0.88

3.530

0.0004 (0.0017)

RRHT = 1.59 [1.26; 2.02]

RRHO = 2.54 [1.58; 4.09]

 

G-T

0.12

-3.630

0.0003 (0.0017)