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Table 3 Comparison of allele frequencies of H63D, S65C and C282Y in the Slovenian population with other European populations

From: Prevalence of H63D, S65C and C282Y hereditary hemochromatosis gene mutations in Slovenian population by an improved high-throughput genotyping assay

Country n H63D (%) p value S65C (%) p value C282Y (%) p value
Slovenia* 1282 12.8   1.8   3.6  
Croatia* [11] 200 14.5 NS 1.8 NS 3.3 NS
Hungary [30] 240 14.4 NS - - 3.4 NSa
Italy – Modena [27] 606 14.9 NS 0.7 0.015 4.7 NS
Italy – Ossola [29] 2100 14.2 NS - - 1.4 < 0.001
Bosnia and Herzegovina* [12] 200 11.3 NS - - 4 NS
Serbia and Montenegro* [26] 318 15.7 NS 1.6 NS 1.6 0.012
The Czech Republic* [9] 481 15 NS 1.2 NS 3.4 NS
Poland* [10] 871 16.2 0.002 - - 3.1 NS
Germany [31] 500 10.8 NS - - 4.5 NS
Denmark [32] 2501 13.3 NS - - 5.7 < 0.001
France [4] 410 14 NS 1.95 NS 7.7 < 0.001
United Kingdom [21] 10556 15.3 < 0,001 - - 8,2 < 0.001
  1. n, number of subjects examined; -, no data; NS not significant. The significance level (α) was set at 0.05.
  2. a Number of examined subjects was 996.
  3. *Population of Slavic origin
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