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Table 3 Comparison of allele frequencies of H63D, S65C and C282Y in the Slovenian population with other European populations

From: Prevalence of H63D, S65C and C282Y hereditary hemochromatosis gene mutations in Slovenian population by an improved high-throughput genotyping assay

Country

n

H63D (%)

p value

S65C (%)

p value

C282Y (%)

p value

Slovenia*

1282

12.8

 

1.8

 

3.6

 

Croatia* [11]

200

14.5

NS

1.8

NS

3.3

NS

Hungary [30]

240

14.4

NS

-

-

3.4

NSa

Italy – Modena [27]

606

14.9

NS

0.7

0.015

4.7

NS

Italy – Ossola [29]

2100

14.2

NS

-

-

1.4

< 0.001

Bosnia and Herzegovina* [12]

200

11.3

NS

-

-

4

NS

Serbia and Montenegro* [26]

318

15.7

NS

1.6

NS

1.6

0.012

The Czech Republic* [9]

481

15

NS

1.2

NS

3.4

NS

Poland* [10]

871

16.2

0.002

-

-

3.1

NS

Germany [31]

500

10.8

NS

-

-

4.5

NS

Denmark [32]

2501

13.3

NS

-

-

5.7

< 0.001

France [4]

410

14

NS

1.95

NS

7.7

< 0.001

United Kingdom [21]

10556

15.3

< 0,001

-

-

8,2

< 0.001

  1. n, number of subjects examined; -, no data; NS not significant. The significance level (α) was set at 0.05.
  2. a Number of examined subjects was 996.
  3. *Population of Slavic origin