Table 5 Population and family-based QTDT results for adult cohort for the most significant variants among CHRM2 gene

rs2350780

PIQ

359

0.26

0.610

0.47 (A)

95

3.62

0.057

3.31 (A)

(136243509)

VIQ

359

0.01

0.920

0.12 (A)

95

0.62

0.431

1.26 (A)

FSIQ

359

0.05

0.823

0.22 (A)

95

1.98

0.159

2.22 (A)

rs1364409

PIQ

350

0.15

0.699

0.35 (A)

92

4.90

0.027

3.13 (A)

(136262573)

VIQ

350

0.05

0.823

0.24 (A)

92

0.02

0.888

1.05 (A)

FSIQ

350

0.05

0.823

0.22 (A)

92

1.25

0.264

0.72 (A)

rs7782965

PIQ

345

0.94

0.332

0.93 (C)

91

5.29

0.021

3.36 (C)

(136274673)

VIQ

345

0.24

0.624

0.49 (C)

91

0.33

0.566

0.16 (C)

FSIQ

345

0.43

0.512

0.67 (C)

91

2.08

0.149

1.60 (C)

rs1378646

PIQ

363

1.08*

0.303

1.05 (A)

90

6.48

0.011

3.77 (A)

(136214872)

VIQ

363

0.61

0.435

0.73 (A)

90

1.27

0.26

1.10 (A)

FSIQ

363

0.76

0.383

0.78 (A)

90

3.65

0.056

2.36 (A)

rs2061174

PIQ

389

4.64*

0.031

2.10 (A)

101

9.14

0.003

6.89 (A)

(136311940)

VIQ

389

0.06

0.806

0.24 (A)

101

0.01

0.920

1.78 (A)

FSIQ

389

0.97

0.325

0.89 (A)

101

1.82

0.177

3.76 (A)

rs17411561

PIQ

306

0.15

0.699

0.47 (T)

79

1.28

0.589

0.69 (C)

(136332728)

VIQ

306

0.42

0.517

0.24 (T)

79

0.15

0.699

0.44 (T)

FSIQ

306

0.02

0.888

0.11 (T)

79

0.60

0.439

0.08 (C)

rs324640

PIQ

386

2.37

0.124

1.40 (A)

123

2.36

0.126

3.05 (A)

(136339536)

VIQ

386

0.02

0.888

0.12 (A)

123

0.21

0.647

1.57 (A)

FSIQ

386

0.54

0.462

0.67 (A)

123

1.04

0.308

2.22 (A)

rs324650

PIQ

369

2.09

0.148

1.28 (A)

117

2.69

0.101

1.69 (T)

(136344201)

VIQ

369

0.15

0.699

0.36 (A)

117

0.00

1.000

0.78 (T)

FSIQ

369

0.13

0.718

0.33 (T)

117

0.58

0.446

0.77 (T)