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Table 2 Risk factors in the probands and their siblings with premature onset CHD

From: Genetic variants of Complement factor H gene are not associated with premature coronary heart disease: a family-based study in the Irish population

Risk factor

Probands (n = 580)

Siblings (n = 786)

Age*

52.0(SD = 7.4)

56.0(SD = 7.8)

Female*

113 (19.5%)

429 (54.6%)

Male*

467 (80.5%)

357 (45.4%)

Non smoker*

116 (20.0%)

328 (41.7%)

Ex smoker*

249 (42.9%)

224 (28.5%)

Current smoker*

215 (37.1%)

234 (29.8%)

Hypertension treatment

148 (25.5%)

177 (22.5%)

Systolic BP ≥ 140 mmHg

30 (5.2%)

239 (30.4%)

Diastolic BP ≥ 95 mmHg

1 (0.2%)

2 (0.3%)

Total hypertension*

179 (30.9%)

418 (53.2%)

Known diabetes*

53 (9.1%)

43 (5.5%)

Total cholesterol (mmol/l)*

4.9(SD = 1.1)

5.8(SD = 1.1)

  1. * P < 0.01, SD – standard deviation.