TY - JOUR AU - Meng, Weihua AU - Hughes, Anne AU - Patterson, Chris C. AU - Belton, Christine AU - Kamaruddin, Muhammad S. AU - Horan, Paul G. AU - Kee, Frank AU - McKeown, Pascal P. PY - 2007 DA - 2007/09/18 TI - Genetic variants of Complement factor H gene are not associated with premature coronary heart disease: a family-based study in the Irish population JO - BMC Medical Genetics SP - 62 VL - 8 IS - 1 AB - The complement factor H (CFH) gene has been recently confirmed to play an essential role in the development of age-related macular degeneration (AMD). There are conflicting reports of its role in coronary heart disease. This study was designed to investigate if, using a family-based approach, there was an association between genetic variants of the CFH gene and risk of early-onset coronary heart disease. SN - 1471-2350 UR - https://doi.org/10.1186/1471-2350-8-62 DO - 10.1186/1471-2350-8-62 ID - Meng2007 ER -