Table 1 Distribution of antihypertensive therapies
Antihypertensive class | N | Number of sibships | Age (yrs) | BMI (kg/m2) | Systolic Blood Pressure (mmHg) | Diastolic Blood Pressure (mmHg) |
|---|---|---|---|---|---|---|
| Â | Â | Â | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) |
| Â | 14 | Â | 54.45 | 30.9 | Â | Â |
No Treatment | 8 | 133 | (11.19) | (5.6) | 149.45 (12.98) | 86.47 (9.40) |
Mono Therapies | Â | Â | Â | Â | Â | Â |
| Â | 16 | Â | 55.28 | 30.7 | Â | Â |
Beta-Blocker | 2 | 147 | (10.38) | (6.7) | 134.77 (16.03) | 79.00 (8.13) |
| Â | Â | Â | 56.61 | 29.5 | Â | Â |
CA-Blocker | 62 | 59 | (9.34) | (5.3) | 143.08 (15.34) | 82.31 (8.99) |
| Â | 12 | Â | 57.48 | 32.0 | Â | Â |
Diuretic | 8 | 122 | (9.56) | (6.6) | 135.27 (12.27) | 79.20 (9.38) |
| Â | 15 | Â | 54.32 | 31.1 | Â | Â |
RAAS Inhibitors | 1 | 136 | (9.52) | (7.3) | 134.13 (15.95) | 80.64 (8.87) |
Combination Therapies | Â | Â | Â | Â | Â | Â |
| Â | 16 | Â | 59.22 | 32.0 | Â | Â |
Beta-Blocker + Diuretic | 7 | 141 | (9.47) | (6.8) | 136.81 (16.25) | 77.55 (9.51) |
| Â | Â | Â | 61.67 | 30.7 | Â | Â |
Beta-Blocker + Other | 73 | 68 | (9.11) | (5.9) | 143.43 (20.40) | 78.41 (9.37) |
| Â | 18 | Â | 58.42 | 31.7 | Â | Â |
Diuretic + Other | 0 | 160 | (9.61) | (6.4) | 135.06 (15.60) | 78.04 (10.01) |
Neither Beta-Blocker | 44 | 42 | 57.70 | 30.9 | 138.81 (18.95) | 80.45 (10.55) |
Nor Diuretic | Â | Â | (9.35) | (6.1) | Â | Â |
| Â | Â | Â | 59.61 | 29.4 | Â | Â |
Other Antihypertensive | 18 | 17 | (10.62) | (4.8) | 141.93 (23.01) | 78.52 (8.81) |
P-value test among drug classes* | Â | Â | <.001 | 0.15 | <.001 | 0.01 |